Scientist/Senior Scientist

OncoMyx is seeking a highly motivated and creative Scientist/Senior Scientist to join a group of researchers evaluating novel oncolytic virus therapies. The candidate will work within project teams to advance research stage programs into pre-clinical development, and provide in-vitro, in-vivo and ex-vivo efficacy and pharmacodynamic data essential to drive projects into clinical development.

Role Responsibilities:

Qualified candidates will possess the following skills and experience.

Plans and executes experiments under minimal supervision that support the initiation and/or advancement of drug candidate projects into the pipeline. Works cross-functionally within the organization to achieve goals. Actively involved in the selection of anti-cancer drug candidates by running both in vitro and/or in vivo efficacy studies.

  • Independently design and perform studies to evaluate the activity and mechanism of action of Immuno-modulatory oncolytic viruses in preclinical models of cancer
  • Must be proficient in aseptic cell culture technique of mammalian cells
  • Experience with protein and molecular biology techniques and assay development such as protein isolation, molecular cloning, ELISA, western blot, qPCR is required
  • Direct experience with construction, production and evaluation of oncolytic viruses is preferred. Experience with Pox viruses is preferred
  • Experience in in vitro assay development including ligand binding, proliferation and cytotoxicity, cell-based reporter assays is required
  • Experience with various in vitro assays applicable to oncology and immuno-oncology such as primary cell isolation and culture, MLR, ADCC, cytotoxicity and reporter assays is recommended
  • Experience with investigating the tumor micro-environments using in vivo or ex vivo techniques such as flow cytometry or Immuno-histochemistry is preferred
  • Ability to manage in vitro and in vivo studies at contract research organizations (CRO) including study design, execution, analysis, and reporting is preferred
  • Prepare detailed technical reports, protocols, quantitative analyses, and maintain appropriate documentation
  • Ability to communicate results at both internal and external meetings
  • This position requires excellent communication skills and ability to perform in a matrix structured work environment and to multi-task and manage multiple projects
  • Proficient in data analysis software such as Microsoft Word, Microsoft Excel, FlowJo, GraphPrism
  • Both effective team player and strong individual contributor, flexible, and able to handle multiple tasks and deliver high quality results under tight timelines

Qualifications:

The level of the position will depend on the qualifications of the selected candidate. Ph.D. degree in a biomedical science or related discipline with at least 2 years post-doctoral industry experience or MS with at least 7 years of experience.  Experience in the Oncolytic Virus or Immuno-Oncology field is recommended. At least 3-5 additional years of experience is required for a senior level.

Location:

Candidate must be located or relocate to Phoenix.

Please send CV and cover letter by email to hr@oncomyx.com. No outside recruiters please.